Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_3976Conserved hypothetical protein. (667 aa)    
Predicted Functional Partners:
MA_3975
Type IV secretion system protein.
 
  
 0.953
tadA1
Type IV secretion system protein.
 
  
 0.789
MA_3528
Conserved hypothetical protein.
  
    0.771
MA_0818
Conserved hypothetical protein.
  
    0.761
MA_4479
Transcriptional regulator, ArsR family.
 
     0.740
flaI
Flagella accessory protein I.
 
  
 0.739
MA_2544
Hypothetical protein (multi-domain).
 
     0.731
rnhB
Ribonuclease Hii; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.717
flaI-2
Flagella accessory protein I.
 
  
 0.715
MA_3754
Transmembrane oligosaccharyl transferase.
 
   
 0.713
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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