Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_3993Conserved hypothetical protein. (199 aa)    
Predicted Functional Partners:
MA_3992
Conserved hypothetical protein.
 
 
 
 0.998
MA_3998
ABC transporter, ATP-binding protein.
 
 
 
 0.989
MA_3996
Conserved hypothetical protein.
 
     0.985
MA_3997
Conserved hypothetical protein; Belongs to the UPF0288 family.
 
   
 0.985
MA_3995
Conserved hypothetical protein.
 
     0.984
MA_4548
Methyl coenzyme M reductase, subunit D.
 
 
 
 0.981
MA_3994
BadF/BadG/BcrA/BcrD ATPase.
 
     0.980
cmd-4
Carboxymuconolactone decarboxylase.
 
     0.960
mcrA
Methyl coenzyme M reductase, subunit alpha; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
 
 
 0.950
MA_4550
Methyl coenzyme M reductase, subunit beta.
 
 
 
 0.929
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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