Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_4040Conserved hypothetical protein. (246 aa)    
Predicted Functional Partners:
MA_4041
Acyl carrier protein synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
 
    0.989
MA_4043
Conserved hypothetical protein.
 
    0.971
MA_4042
acetyl-CoA C-acyltransferase.
  
    0.966
cyaB
Adenylate cyclase.
 
     0.904
MA_4039
Conserved hypothetical protein.
       0.869
MA_1408
Conserved hypothetical protein.
 
     0.716
MA_3711
Conserved hypothetical protein.
  
     0.697
carS
Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
     0.674
MA_4266
Conserved hypothetical protein.
  
     0.656
tgt-2
Archaeosine tRNA-ribosyltransferase.
  
     0.636
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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