STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MA_4064Hypothetical protein; Belongs to the AAA ATPase family. (428 aa)    
Predicted Functional Partners:
phnP
ATP-binding protein PhnP.
 
     0.893
rpl40e
Ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
 
 0.752
pan
Proteasome-activating nucleotidase; Belongs to the AAA ATPase family.
 
0.726
pan-2
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
 
0.718
MA_3684
Conserved hypothetical protein.
 
     0.700
map
Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
 
 0.691
ybtP
Iron ABC transporter; Permease and ATP-binding protein.
 
 0.680
MA_2939
Hypothetical protein.
 
 0.680
MA_3528
Conserved hypothetical protein.
 
    0.672
psmB
Multicatalytic endopeptidase complex, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 0.670
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.