Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_4074phenylacetyl-CoA ligase. (459 aa)    
Predicted Functional Partners:
paaI
Phenylacetic acid degradation protein.
 
  
 0.586
MA_0705
Aldehyde dehydrogenase.
  
 
 0.526
MA_1355
Aldehyde dehydrogenase.
  
 
 0.526
aldH
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
  
 
 0.526
aldH6
Aldehyde dehydrogenase (NAD(P)+).
  
 
 0.526
MA_3854
Acetolactate synthase, small subunit.
 
   0.489
MA_4075
Transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.
     
 0.430
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: low (38%) [HD]