Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_4083NaH antiporter protein. (393 aa)    
Predicted Functional Partners:
MA_3020
Conserved hypothetical protein.
   
 
 0.828
MA_4084
Hypothetical protein (multi-domain).
    
 0.737
MA_2677
Conserved hypothetical protein.
       0.613
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.534
MA_0147
NADPH:quinone reductase.
  
 
 0.503
MA_0326
Quinone reductase.
  
 
 0.503
hisS
histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
     0.454
MA_3108
Glutathione-regulated potassium-efflux system protein.
 
  
0.436
kefC
Glutathione-regulated potassium-efflux system protein.
 
  
0.431
MA_4087
Molybdenum cofactor biosynthesis protein MoeA2.
  
  
 0.420
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: low (38%) [HD]