Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_4097Conserved hypothetical protein; Belongs to the UPF0235 family. (123 aa)    
Predicted Functional Partners:
MA_4098
Conserved hypothetical protein.
 
     0.916
trmY
Conserved hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
 
     0.713
MA_1981
Conserved hypothetical protein.
  
     0.667
MA_0067
Conserved hypothetical protein.
  
     0.644
MA_4096
Predicted protein.
       0.625
glyS
glycyl-tRNA synthetase.
       0.607
MA_0647
Predicted protein.
 
     0.570
MA_1413
Sm protein.
 
     0.568
murD
UDP-N-acetylmuramoylalanine-D-glutamate ligase; Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the activation the g-propionate side chain of 15,17(3)-seco-F430-17(3)-acid (seco-F430) for intramolecular C-C bond formation to yield the carbocyclic F ring of coenzyme F430. Belongs to the MurCDEF family.
 
     0.557
MA_0695
Conserved hypothetical protein.
 
     0.548
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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