Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
rpl18aRibosomal protein LX. (61 aa)    
Predicted Functional Partners:
rpl2
Ribosomal protein L2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 0.999
rpl18
Ribosomal protein L18p; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
 0.999
rpl30e
Ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family.
  
 0.999
rpl21e
Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
 0.999
rpl24e
Ribosomal protein L24e; Binds to the 23S rRNA.
  
 0.999
rpl40e
Ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.999
rpl31e
Ribosomal protein L31e; Belongs to the eukaryotic ribosomal protein eL31 family.
  
 0.999
rps19e
Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
 
 0.999
rpl18e
Ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family.
   
 0.998
rpl13
Ribosomal protein L13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 0.998
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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