Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_4121Predicted protein. (80 aa)    
Predicted Functional Partners:
MA_1736
Mov34 family protein.
  
 0.916
psmB
Multicatalytic endopeptidase complex, subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 0.884
psmA
Multicatalytic endopeptidase complex, subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 0.875
MA_3330
Conserved hypothetical protein.
  
 0.875
rpl40e
Ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.827
rad50
Purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
   
 
 0.684
rps3
Ribosomal protein S3p; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 
 0.553
MA_0916
Erythrocyte band 7 integral membrane protein.
  
 
 0.540
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
   
 
 0.538
rps6e
Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 
 0.534
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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