Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_4147Metallo-beta-lactamase family protein. (500 aa)    
Predicted Functional Partners:
MA_4091
Hypothetical protein (multi-domain).
  
     0.603
MA_4146
Predicted protein.
       0.572
MA_0974
Predicted protein.
  
     0.571
MA_2496
Predicted protein.
  
     0.522
MA_0777
Signal-transducing histidine kinase.
  
     0.487
MA_4148
Type 2 phosphatidic acid phosphatase Pap2.
       0.478
MA_3270
Predicted protein.
  
     0.456
MA_1863
Transcriptional regulator, MarR family.
  
     0.444
MA_3321
Conserved hypothetical protein.
 
     0.406
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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