Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MA_4264Isopropylmalate/homocitrate/citramalate synthase family protein. (443 aa)    
Predicted Functional Partners:
MA_0250
Aconitate hydratase.
  
 0.936
MA_0249
Citrate (si)-synthase.
  
 
 0.923
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.918
pycA
Pyruvate carboxylase subunit A.
  
 
 0.917
porA
Pyruvate synthase, subunit alpha.
  
 
 0.913
MA_3075
2-oxoacid ferredoxin oxidoreductase, subunit alpha.
  
 
 0.913
porB
Pyruvate synthase, subunit beta.
  
 
 0.912
porB-2
Pyruvate synthase, beta subunit.
  
 
 0.912
MA_3076
2-oxoacid ferredoxin oxidoreductase, subunit beta.
  
 
 0.912
porG
Pyruvate synthase, subunit gamma.
    
 0.909
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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