Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MA_4345Conserved hypothetical protein. (455 aa)    
Predicted Functional Partners:
smtB
Efflux system transcriptional regulator, ArsR family.
  
  
 0.939
MA_4343
Cobalt transport family protein.
  
    0.730
MA_4342
Membrane associated ATPase; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
       0.712
MA_4340
Biotin synthesis BioY protein.
       0.703
ecfA
Membrane associated ATPase; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
       0.703
MA_4346
Hypothetical protein (multi-domain).
       0.678
MA_3938
Conserved hypothetical protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.
 
  
 0.473
MA_3942
Conserved hypothetical protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.
 
  
 0.452
MA_3939
Conserved hypothetical protein.
 
    0.413
MA_3285
Conserved hypothetical protein.
  
    0.405
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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