Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_4369Hydrogenase-3 subunit (EchB-like protein). (313 aa)    
Predicted Functional Partners:
MA_4368
Hydrogenase-3, subunit C (HycC-like protein).
 
 0.999
MA_4373
Hydrogenase-3, subunit G (HycG-like protein).
 
 0.999
MA_4372
Hydrogenase-3, subunit E (HycE-like protein).
 
 
 0.998
MA_4371
Hydrogenase-3 subunit (EchA-like protein).
 
 
 0.995
MA_4370
Conserved hypothetical protein.
 
  
 0.988
fpoI
F(420)H(2) dehydrogenase, subunit FpoI.
  
 
 0.966
mrpB
Multiple resistance/pH regulation related protein B (Na+/H+ antiporter).
  
   0.909
mrpD
Multiple resistance/pH regulation related protein D (Na+/H+ antiporter).
 
 
 0.894
mrpE
Multiple resistance/pH regulation related protein E (Na+/H+ antiporter).
   
 
 0.887
fpoC
F(420)H(2) dehydrogenase, subunit FpoC.
  
 
 0.872
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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