Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_4371Hydrogenase-3 subunit (EchA-like protein). (516 aa)    
Predicted Functional Partners:
MA_4369
Hydrogenase-3 subunit (EchB-like protein).
 
 
 0.995
MA_4372
Hydrogenase-3, subunit E (HycE-like protein).
 
 
 0.995
MA_4373
Hydrogenase-3, subunit G (HycG-like protein).
 
 
 0.991
MA_4370
Conserved hypothetical protein.
 
  
 0.982
mrpC
Multiple resistance/pH regulation related protein C (Na+/H+ antiporter).
 
 
 0.962
mrpE
Multiple resistance/pH regulation related protein E (Na+/H+ antiporter).
 
 
 0.950
mrpG
Multiple resistance/pH regulation related protein G (Na+/H+ antiporter).
 
 
 0.943
mrpB
Multiple resistance/pH regulation related protein B (Na+/H+ antiporter).
 
 
 0.941
mrpF
Multiple resistance/pH regulation related protein F (Na+/H+ antiporter).
 
 
 0.914
fpoL
F(420)H(2) dehydrogenase, subunit FpoL.
 
 
0.905
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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