Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MA_4380Conserved hypothetical protein. (539 aa)    
Predicted Functional Partners:
mtaA-2
methylcobamide:CoM methyltransferase isozyme M.
 
    0.839
cmtM-3
methylcobamide:CoM methyltransferase isozyme M.
 
    0.826
cmtA
methylcobalamin:CoM methyltransferase isozyme A.
 
    0.751
mtaA
methylcobamide:CoM methyltransferase isozyme M.
 
    0.746
cmtM-6
methylcobamide:CoM methyltransferase isozyme M.
 
    0.737
cmtM-2
methylcobamide:CoM methyltransferase isozyme M.
 
    0.735
mtbA
methylcobalamin:CoM methyltransferase isozyme A; Methyltransferase involved in methanogenesis from methylamines methanol pathway. Catalyzes the transfer of the methyl group from the methylated corrinoid protein MtmC (MtmC1 or MtmC2) to coenzyme M, forming the substrate for coenzyme-B sulfoethylthiotransferase (By similarity); Belongs to the uroporphyrinogen decarboxylase family. MtbA/MtaA subfamily.
 
    0.726
MA_0827
Predicted protein.
 
     0.723
cmtM-4
methylcobamide:CoM methyltransferase isozyme M.
 
    0.717
cmtM
methylcobamide:CoM methyltransferase isozyme M.
 
    0.709
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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