Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MA_4382CobW protein. (451 aa)    
Predicted Functional Partners:
mtaA-2
methylcobamide:CoM methyltransferase isozyme M.
 
  
 0.738
map
Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
   
 
 0.711
mtaA
methylcobamide:CoM methyltransferase isozyme M.
 
  
 0.709
MA_4380
Conserved hypothetical protein.
 
    0.648
MA_3972
Conserved hypothetical protein.
 
    0.641
cysS
cysteinyl-tRNA synthetase.
 
  
 0.635
ramA
Methylamine methyltransferase corrinoid activation protein.
 
    0.633
MA_0849
Hypothetical protein (multi-domain).
 
    0.624
rps14
Ribosomal protein S14p; Binds 16S rRNA, required for the assembly of 30S particles.
  
 
 0.591
mptA
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
  
  
 0.568
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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