Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MA_4384Hypothetical protein (multi-domain). (631 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
 
 0.589
mttB-2
Trimethylamine methyltransferase; Catalyzes the transfer of a methyl group from trimethylamine to the corrinoid cofactor of MttC.
 
 
 
 0.580
mttB
Trimethylamine methyltransferase; Catalyzes the transfer of a methyl group from trimethylamine to the corrinoid cofactor of MttC.
 
 
 
 0.578
mer
F420-dependent N5,N10-methylene-tetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
     
 0.576
MA_0849
Hypothetical protein (multi-domain).
 
  
 0.566
MA_3972
Conserved hypothetical protein.
 
  
 0.560
ramA
Methylamine methyltransferase corrinoid activation protein.
 
  
 0.557
MA_4380
Conserved hypothetical protein.
 
  
 0.557
MA_3020
Conserved hypothetical protein.
  
  
 0.545
mtaB1
Methanol-5-hydroxybenzimidazolylcobamide co-methyltransferase, isozyme 1.
   
 
 0.504
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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