Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MA_4541Mrr restriction system protein. (303 aa)    
Predicted Functional Partners:
comDE
Sulfopyruvate decarboxylase; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde. Is not able to decarboxylate the analogous compounds 2-oxoglutarate or 2-oxosuberate.
   
    0.789
MA_2963
Iron-sulfur cluster binding protein.
  
    0.784
MA_4540
Conserved hypothetical protein.
       0.705
hsdM
Site-specific DNA-methyltransferase (adenine-specific), subunit M.
 
  
 0.623
hsdR
Type I site-specific deoxyribonuclease protein R.
 
  
 0.595
MA_4622
Conserved hypothetical protein.
  
    0.594
MA_2106
Hypothetical protein (multi-domain).
 
  
 0.591
MA_0287
Conserved hypothetical protein.
  
    0.582
MA_2207
Conserved hypothetical protein.
  
    0.581
MA_2057
Conserved hypothetical protein.
  
    0.579
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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