Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_4576Hth5 family protein. (230 aa)    
Predicted Functional Partners:
cdc48-2
Cell division control protein 48.
     
 0.828
MA_3684
Conserved hypothetical protein.
  
     0.717
MA_4574
Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family.
 
   
 0.716
MA_4573
Conserved hypothetical protein.
 
   
 0.698
MA_1150
Predicted protein.
  
     0.683
MA_1394
Conserved hypothetical protein.
  
     0.671
MA_1372
Conserved hypothetical protein; Belongs to the UPF0212 family.
  
     0.658
pfdA
Prefoldin, subunit alpha; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
   
 0.658
MA_2517
Conserved hypothetical protein.
  
     0.654
tgt-2
Archaeosine tRNA-ribosyltransferase.
  
     0.653
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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