Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
fwdE-2Formylmethanofuran dehydrogenase, subunit E. (217 aa)    
Predicted Functional Partners:
oppA-7
Oligopeptide ABC transporter, solute-binding protein.
 
     0.807
ftr
Formylmethanofuran-tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
     
 0.786
oppB-8
Oligopeptide ABC transporter, permease protein.
 
     0.777
cooS-2
Carbon-monoxide dehydrogenase, catalytic subunit; CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH).
  
  
  0.762
MA_4023
Cobalamin biosynthesis protein.
  
    0.748
oppC-7
Oligopeptide ABC transporter, permease protein.
       0.744
oppD-7
Oligopeptide ABC transporter, ATP-binding protein.
       0.741
oppF-6
Oligopeptide ABC transporter, ATP-binding protein.
       0.740
cooS
Carbon-monoxide dehydrogenase, catalytic subunit; CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH).
  
  
  0.714
cooF
Carbon-monoxide dehydrogenase, Fe-S subunit.
  
  
  0.695
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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