STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MA_4631D-lactate dehydrogenase. (503 aa)    
Predicted Functional Partners:
MA_4630
Iron-sulfur binding reductase.
  
 0.993
MA_2967
Haloacid dehalogenase-like hydrolase.
    
 0.929
MA_3544
Conserved hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
 0.909
idi
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 0.860
MA_0167
Conserved hypothetical protein.
  
 
 0.798
fpoC
F(420)H(2) dehydrogenase, subunit FpoC.
 
 
 
 0.759
hdrD-2
Heterodisulfide reductase, subunit D; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 0.715
fpoB
F(420)H(2) dehydrogenase, subunit FpoB; Belongs to the complex I 20 kDa subunit family.
  
 
 0.713
hdrD
Heterodisulfide reductase, subunit D.
  
 0.710
fpoN
F(420)H(2) dehydrogenase, subunit FpoN.
   
 
 0.677
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
Server load: low (22%) [HD]