Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MA_4643Hypothetical protein. (1414 aa)    
Predicted Functional Partners:
cbiA1
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
 
 0.939
MA_2084
cob(I)alamin adenosyltransferase.
 
 
 0.932
MA_4641
MotA/TolQ/ExbB proton channel family protein.
 
  
 0.876
MA_0877
Magnesium-chelatase subunit.
 
  
 0.856
MA_4642
Conserved hypothetical protein.
 
    0.848
MA_4426
MotA/TolQ/ExbB proton channel family protein.
 
  
 0.793
MA_0344
MotA/TolQ/ExbB proton channel family protein.
 
  
 0.786
MA_0345
Conserved hypothetical protein.
 
    0.718
MA_4425
Conserved hypothetical protein.
 
    0.715
MA_4640
Conserved hypothetical protein.
 
    0.681
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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