Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MA_4650Conserved hypothetical protein. (281 aa)    
Predicted Functional Partners:
MA_4651
Conserved hypothetical protein.
 
 
  
0.977
rps2
Ribosomal protein S2p; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.931
rpl6
Ribosomal protein L6p; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
  
   0.926
rps9
Ribosomal protein S9p; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.924
rps11
Ribosomal protein S11p; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 
 0.924
rpl18e
Ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family.
  
 
 0.923
rps15
Ribosomal protein S15p.
  
   0.923
rpl7ae
Ribosomal protein L7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 
 0.923
rpl22
Ribosomal protein L22p; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
 
 0.920
rpl5
Ribosomal protein L5p; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
 
   0.920
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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