Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MA_4659Conserved hypothetical protein; Belongs to the UPF0201 family. (164 aa)    
Predicted Functional Partners:
MA_4660
Conserved hypothetical protein; Belongs to the UPF0200 family.
 
    0.913
MA_4658
Conserved hypothetical protein.
 
    0.895
MA_1278
Conserved hypothetical protein.
 
   
 0.736
cca
tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
 
     0.620
MA_2881
GufA protein.
       0.617
MA_3997
Conserved hypothetical protein; Belongs to the UPF0288 family.
  
    0.580
MA_0656
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
       0.532
rps3ae
Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
 
     0.520
MA_1783
Conserved hypothetical protein.
  
   
 0.519
MA_1279
Conserved hypothetical protein.
  
     0.515
Your Current Organism:
Methanosarcina acetivorans
NCBI taxonomy Id: 188937
Other names: M. acetivorans C2A, Methanosarcina acetivorans C2A, Methanosarcina acetivorans str. C2A
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