Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OOQ54926.1Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)    
Predicted Functional Partners:
OOQ54245.1
Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.947
OOQ47962.1
DNA repair ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.947
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.931
OOQ49564.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.924
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.834
OOQ53942.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.821
OOQ46746.1
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.798
OOQ54927.1
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.794
OOQ49070.1
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.785
OOQ46756.1
Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.785
Your Current Organism:
Streptomyces antibioticus
NCBI taxonomy Id: 1890
Other names: ATCC 23879, ATCC 8663, Actinomyces antibioticus, BCRC 12164, CBS 478.48, CBS 659.68, CCM 3159, CCRC 12164, CCRC:12164, CECT 3225, DSM 40234, IFO 12838, IMET 40227, ISP 5234, JCM 4620, KCTC 9688, LMG 5966, LMG:5966, NBRC 12838, NCIMB 8504, NRRL B-2770, NRRL-ISP 5234, S. antibioticus, Streptomyces antibioticus subsp. antibioticus, VKM Ac-964
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.