Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OOQ55452.1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)    
Predicted Functional Partners:
OOQ55085.1
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.729
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.596
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.595
OOQ55240.1
LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
  
     0.587
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.568
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.555
OOQ47905.1
LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.506
OOQ54593.1
LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.499
OOQ52341.1
RNA polymerase subunit sigma-70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
   0.431
OOQ50898.1
RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
   0.431
Your Current Organism:
Streptomyces antibioticus
NCBI taxonomy Id: 1890
Other names: ATCC 23879, ATCC 8663, Actinomyces antibioticus, BCRC 12164, CBS 478.48, CBS 659.68, CCM 3159, CCRC 12164, CCRC:12164, CECT 3225, DSM 40234, IFO 12838, IMET 40227, ISP 5234, JCM 4620, KCTC 9688, LMG 5966, LMG:5966, NBRC 12838, NCIMB 8504, NRRL B-2770, NRRL-ISP 5234, S. antibioticus, Streptomyces antibioticus subsp. antibioticus, VKM Ac-964
Server load: low (16%) [HD]