Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OOQ55108.1Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)    
Predicted Functional Partners:
OOQ50968.1
Aminoacylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.579
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.574
OOQ55445.1
Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.566
OOQ55107.1
Acetyl xylan esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.562
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.516
OOQ47646.1
Peptidase S12; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.475
OOQ49235.1
Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.425
OOQ54872.1
RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.419
Your Current Organism:
Streptomyces antibioticus
NCBI taxonomy Id: 1890
Other names: ATCC 23879, ATCC 8663, Actinomyces antibioticus, BCRC 12164, CBS 478.48, CBS 659.68, CCM 3159, CCRC 12164, CCRC:12164, CECT 3225, DSM 40234, IFO 12838, IMET 40227, ISP 5234, JCM 4620, KCTC 9688, LMG 5966, LMG:5966, NBRC 12838, NCIMB 8504, NRRL B-2770, NRRL-ISP 5234, S. antibioticus, Streptomyces antibioticus subsp. antibioticus, VKM Ac-964
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