STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OOQ55460.1LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)    
Predicted Functional Partners:
OOQ52806.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.857
OOQ47915.1
GltA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.857
OOQ55201.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.847
OOQ55200.1
ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.755
OOQ46780.1
Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.727
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
   0.686
pheT
phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
    
   0.669
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
   0.635
OOQ55039.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.628
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.611
Your Current Organism:
Streptomyces antibioticus
NCBI taxonomy Id: 1890
Other names: ATCC 23879, ATCC 8663, Actinomyces antibioticus, BCRC 12164, CBS 478.48, CBS 659.68, CCM 3159, CCRC 12164, CCRC:12164, CECT 3225, DSM 40234, IFO 12838, IMET 40227, ISP 5234, JCM 4620, KCTC 9688, LMG 5966, LMG:5966, NBRC 12838, NCIMB 8504, NRRL B-2770, NRRL-ISP 5234, S. antibioticus, Streptomyces antibioticus subsp. antibioticus, VKM Ac-964
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