| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OOQ48710.1 | OOQ49555.1 | AFM16_27260 | AFM16_25325 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | 0.825 |
| OOQ48710.1 | OOQ49570.1 | AFM16_27260 | AFM16_25405 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine biosynthesis protein ThiF; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.712 |
| OOQ48710.1 | OOQ52883.1 | AFM16_27260 | AFM16_11000 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.541 |
| OOQ48710.1 | OOQ52884.1 | AFM16_27260 | AFM16_11005 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.966 |
| OOQ48710.1 | fbiC | AFM16_27260 | AFM16_16995 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-phospho-L-lactate guanylyltransferase; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.450 |
| OOQ48710.1 | mqnC | AFM16_27260 | AFM16_22460 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dehypoxanthine futalosine cyclase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.450 |
| OOQ48710.1 | mqnE | AFM16_27260 | AFM16_22240 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Radical SAM protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.450 |
| OOQ48710.1 | thiC | AFM16_27260 | AFM16_19465 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.995 |
| OOQ48710.1 | thiE | AFM16_27260 | AFM16_10980 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
| OOQ48710.1 | thiG | AFM16_27260 | AFM16_11010 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.967 |
| OOQ49555.1 | OOQ48710.1 | AFM16_25325 | AFM16_27260 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.825 |
| OOQ49555.1 | OOQ52883.1 | AFM16_25325 | AFM16_11000 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Glycine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.532 |
| OOQ49555.1 | OOQ52884.1 | AFM16_25325 | AFM16_11005 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.988 |
| OOQ49555.1 | fbiC | AFM16_25325 | AFM16_16995 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | 2-phospho-L-lactate guanylyltransferase; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.542 |
| OOQ49555.1 | mqnC | AFM16_25325 | AFM16_22460 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Dehypoxanthine futalosine cyclase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.542 |
| OOQ49555.1 | mqnE | AFM16_25325 | AFM16_22240 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Radical SAM protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.542 |
| OOQ49555.1 | thiC | AFM16_25325 | AFM16_19465 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.860 |
| OOQ49555.1 | thiE | AFM16_25325 | AFM16_10980 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.918 |
| OOQ49555.1 | thiG | AFM16_25325 | AFM16_11010 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.989 |
| OOQ49570.1 | OOQ48710.1 | AFM16_25405 | AFM16_27260 | Thiamine biosynthesis protein ThiF; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.712 |
