Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
OOQ51887.1Translocation protein TolB; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.776
OOQ54851.1
Anti-sigma regulatory factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.665
OOQ49123.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.621
OOQ48963.1
uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.581
OOQ51888.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
OOQ48518.1
Excisionase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.513
OOQ52745.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.509
OOQ48554.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.506
OOQ52234.1
dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.458
OOQ49114.1
Excisionase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.458
Your Current Organism:
Streptomyces antibioticus
NCBI taxonomy Id: 1890
Other names: ATCC 23879, ATCC 8663, Actinomyces antibioticus, BCRC 12164, CBS 478.48, CBS 659.68, CCM 3159, CCRC 12164, CCRC:12164, CECT 3225, DSM 40234, IFO 12838, IMET 40227, ISP 5234, JCM 4620, KCTC 9688, LMG 5966, LMG:5966, NBRC 12838, NCIMB 8504, NRRL B-2770, NRRL-ISP 5234, S. antibioticus, Streptomyces antibioticus subsp. antibioticus, VKM Ac-964
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