Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
OOQ52364.1Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.813
OOQ52036.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.754
OOQ51201.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.723
OOQ52037.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family.
 
     0.702
OOQ55246.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.696
OOQ53570.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.696
OOQ47971.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.696
OOQ49409.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.670
OOQ54907.1
Chitosanase; Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
  
     0.580
OOQ52803.1
Chitosanase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.547
Your Current Organism:
Streptomyces antibioticus
NCBI taxonomy Id: 1890
Other names: ATCC 23879, ATCC 8663, Actinomyces antibioticus, BCRC 12164, CBS 478.48, CBS 659.68, CCM 3159, CCRC 12164, CCRC:12164, CECT 3225, DSM 40234, IFO 12838, IMET 40227, ISP 5234, JCM 4620, KCTC 9688, LMG 5966, LMG:5966, NBRC 12838, NCIMB 8504, NRRL B-2770, NRRL-ISP 5234, S. antibioticus, Streptomyces antibioticus subsp. antibioticus, VKM Ac-964
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