Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OOQ50010.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)    
Predicted Functional Partners:
OOQ50009.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.768
OOQ50011.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.718
OOQ51867.1
Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.710
OOQ50016.1
Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.710
OOQ48546.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.684
disA
DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
     0.654
OOQ48643.1
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.576
OOQ48819.1
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.548
OOQ49288.1
Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.540
OOQ50149.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.531
Your Current Organism:
Streptomyces antibioticus
NCBI taxonomy Id: 1890
Other names: ATCC 23879, ATCC 8663, Actinomyces antibioticus, BCRC 12164, CBS 478.48, CBS 659.68, CCM 3159, CCRC 12164, CCRC:12164, CECT 3225, DSM 40234, IFO 12838, IMET 40227, ISP 5234, JCM 4620, KCTC 9688, LMG 5966, LMG:5966, NBRC 12838, NCIMB 8504, NRRL B-2770, NRRL-ISP 5234, S. antibioticus, Streptomyces antibioticus subsp. antibioticus, VKM Ac-964
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