Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OOQ49288.1Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)    
Predicted Functional Partners:
trpS-2
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.740
OOQ52599.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.591
OOQ50341.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.582
OOQ46900.1
Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.574
OOQ50726.1
acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.541
OOQ50010.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.540
OOQ52598.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.538
OOQ49293.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.517
disA
DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
     0.473
OOQ52872.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.464
Your Current Organism:
Streptomyces antibioticus
NCBI taxonomy Id: 1890
Other names: ATCC 23879, ATCC 8663, Actinomyces antibioticus, BCRC 12164, CBS 478.48, CBS 659.68, CCM 3159, CCRC 12164, CCRC:12164, CECT 3225, DSM 40234, IFO 12838, IMET 40227, ISP 5234, JCM 4620, KCTC 9688, LMG 5966, LMG:5966, NBRC 12838, NCIMB 8504, NRRL B-2770, NRRL-ISP 5234, S. antibioticus, Streptomyces antibioticus subsp. antibioticus, VKM Ac-964
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