PROFUN_01040 protein (Planoprotostelium fungivorum)

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Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

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PROFUN_01040

Protein NLRC3-like. (739 aa)

Predicted Functional Partners:

PROFUN_05594

0.590

PROFUN_00025

0.516

PROFUN_07441

0.459

PROFUN_10412

0.447

PROFUN_15626

0.438

PROFUN_14840

0.438

PROFUN_04127

0.430

PROFUN_04626

0.430

PROFUN_07882

0.406

Your Current Organism:

Planoprotostelium fungivorum

NCBI taxonomy Id: 1890364
Other names: P. fungivorum, Planoprotostelium fungivorum Hillmann, Ferling, Novohradska & Gloeckner 2017, Protostelium sp. Jena Gg-2016a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PROFUN_00025	PROFUN_01040	A0A2P6P0E6	A0A2P6N4J0	Ubiquitin.	Protein NLRC3-like.	0.516
PROFUN_00025	PROFUN_04127	A0A2P6P0E6	A0A2P6NJK0	Ubiquitin.	Ubiquitin-like domain-containing protein.	0.991
PROFUN_00025	PROFUN_04626	A0A2P6P0E6	A0A2P6NUF7	Ubiquitin.	Ribosomal protein L40.	0.996
PROFUN_00025	PROFUN_05594	A0A2P6P0E6	A0A2P6N067	Ubiquitin.	Uncharacterized protein.	0.999
PROFUN_00025	PROFUN_07441	A0A2P6P0E6	A0A2P6NLG0	Ubiquitin.	CD2-associated protein.	0.984
PROFUN_00025	PROFUN_07882	A0A2P6P0E6	A0A2P6NL47	Ubiquitin.	Ephrin type-A receptor 10-like.	0.727
PROFUN_01040	PROFUN_00025	A0A2P6N4J0	A0A2P6P0E6	Protein NLRC3-like.	Ubiquitin.	0.516
PROFUN_01040	PROFUN_04127	A0A2P6N4J0	A0A2P6NJK0	Protein NLRC3-like.	Ubiquitin-like domain-containing protein.	0.430
PROFUN_01040	PROFUN_04626	A0A2P6N4J0	A0A2P6NUF7	Protein NLRC3-like.	Ribosomal protein L40.	0.430
PROFUN_01040	PROFUN_05594	A0A2P6N4J0	A0A2P6N067	Protein NLRC3-like.	Uncharacterized protein.	0.590
PROFUN_01040	PROFUN_07441	A0A2P6N4J0	A0A2P6NLG0	Protein NLRC3-like.	CD2-associated protein.	0.459
PROFUN_01040	PROFUN_07882	A0A2P6N4J0	A0A2P6NL47	Protein NLRC3-like.	Ephrin type-A receptor 10-like.	0.406
PROFUN_01040	PROFUN_10412	A0A2P6N4J0	A0A2P6NE08	Protein NLRC3-like.	DNA-binding protein RFX2 isoform 1.	0.447
PROFUN_01040	PROFUN_14840	A0A2P6N4J0	A0A2P6MYK1	Protein NLRC3-like.	Uncharacterized protein.	0.438
PROFUN_01040	PROFUN_15626	A0A2P6N4J0	A0A2P6MVB9	Protein NLRC3-like.	WD_REPEATS_REGION domain-containing protein.	0.438
PROFUN_04127	PROFUN_00025	A0A2P6NJK0	A0A2P6P0E6	Ubiquitin-like domain-containing protein.	Ubiquitin.	0.991
PROFUN_04127	PROFUN_01040	A0A2P6NJK0	A0A2P6N4J0	Ubiquitin-like domain-containing protein.	Protein NLRC3-like.	0.430
PROFUN_04127	PROFUN_05594	A0A2P6NJK0	A0A2P6N067	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.982
PROFUN_04127	PROFUN_07441	A0A2P6NJK0	A0A2P6NLG0	Ubiquitin-like domain-containing protein.	CD2-associated protein.	0.987
PROFUN_04127	PROFUN_07882	A0A2P6NJK0	A0A2P6NL47	Ubiquitin-like domain-containing protein.	Ephrin type-A receptor 10-like.	0.674

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Network Stats

number of nodes:

11

number of edges:

25

average node degree:

4.55

avg. local clustering coefficient:

0.879

expected number of edges:

10

PPI enrichment p-value:

8.91e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015940

Pantothenate biosynthetic process

3 of 7

2.58

1.81

0.00046

GO:0072330

Monocarboxylic acid biosynthetic process

4 of 111

1.5

1.04

0.0051

GO:0019752

Carboxylic acid metabolic process

6 of 554

0.98

0.67

0.0090

GO:0044281

Small molecule metabolic process

8 of 1051

0.83

0.64

0.0028

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016903

Oxidoreductase activity, acting on the aldehyde or oxo group of donors

3 of 22

2.08

1.27

0.0037

GO:0004029

Aldehyde dehydrogenase (NAD+) activity

2 of 8

2.34

0.77

0.0397

GO:0003824

Catalytic activity

11 of 4151

0.37

0.26

0.0397

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:13320

Coenzyme A biosynthesis, and Pantothenate metabolic process

4 of 12

2.47

2.91

2.87e-06

CL:13321

Pantothenate metabolic process, and Ketopantoate reductase PanE/ApbA

3 of 6

2.65

2.31

5.28e-05

CL:13126

Mixed, incl. Metabolism of nucleotides, and Vitamin biosynthetic process

5 of 109

1.61

1.77

5.28e-05

CL:11098

acetate-CoA ligase activity, and Aldehyde dehydrogenase family

2 of 6

2.47

1.06

0.0117

CL:10969

Mixed, incl. Valine, leucine and isoleucine degradation, and Peroxisomal lipid metabolism

3 of 80

1.52

0.76

0.0270

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00770

Pantothenate and CoA biosynthesis

6 of 49

2.03

3.87

1.65e-09

map00410

beta-Alanine metabolism

3 of 33

1.91

1.69

0.00035

map01110

Biosynthesis of secondary metabolites

7 of 812

0.88

0.78

0.00035

map01100

Metabolic pathways

11 of 2836

0.54

0.46

9.74e-05

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