PROFUN_10829 protein (Planoprotostelium fungivorum)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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Score

PROFUN_10829

Spatacsin_C domain-containing protein. (2581 aa)

Predicted Functional Partners:

PROFUN_10164

0.582

PROFUN_02281

0.582

PROFUN_09281

0.561

PROFUN_14049

0.559

PROFUN_10576

0.559

PROFUN_05600

0.521

PROFUN_02591

0.510

PROFUN_15491

0.509

PROFUN_12179

0.509

PROFUN_05347

0.508

Your Current Organism:

Planoprotostelium fungivorum

NCBI taxonomy Id: 1890364
Other names: P. fungivorum, Planoprotostelium fungivorum Hillmann, Ferling, Novohradska & Gloeckner 2017, Protostelium sp. Jena Gg-2016a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PROFUN_02281	PROFUN_10829	A0A2P6NYG7	A0A2P6NCP3	Uncharacterized protein.	Spatacsin_C domain-containing protein.	0.582
PROFUN_02591	PROFUN_05347	A0A2P6MPH2	A0A2P6NRC1	SAC domain-containing protein.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.515
PROFUN_02591	PROFUN_10829	A0A2P6MPH2	A0A2P6NCP3	SAC domain-containing protein.	Spatacsin_C domain-containing protein.	0.510
PROFUN_02591	PROFUN_12179	A0A2P6MPH2	A0A2P6N8H0	SAC domain-containing protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.531
PROFUN_02591	PROFUN_14049	A0A2P6MPH2	A0A2P6N248	SAC domain-containing protein.	Cyclin-G-associated kinase.	0.747
PROFUN_02591	PROFUN_15491	A0A2P6MPH2	A0A2P6MW00	SAC domain-containing protein.	LsmAD domain-containing protein.	0.512
PROFUN_05347	PROFUN_02591	A0A2P6NRC1	A0A2P6MPH2	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	SAC domain-containing protein.	0.515
PROFUN_05347	PROFUN_10829	A0A2P6NRC1	A0A2P6NCP3	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Spatacsin_C domain-containing protein.	0.508
PROFUN_05347	PROFUN_12179	A0A2P6NRC1	A0A2P6N8H0	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.543
PROFUN_05347	PROFUN_14049	A0A2P6NRC1	A0A2P6N248	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Cyclin-G-associated kinase.	0.696
PROFUN_05347	PROFUN_15491	A0A2P6NRC1	A0A2P6MW00	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	LsmAD domain-containing protein.	0.510
PROFUN_05600	PROFUN_10576	A0A2P6N078	A0A2P6NCZ1	Spartin-like protein.	Alpha/beta hydrolase fold-1 domain-containing protein.	0.520
PROFUN_05600	PROFUN_10829	A0A2P6N078	A0A2P6NCP3	Spartin-like protein.	Spatacsin_C domain-containing protein.	0.521
PROFUN_09281	PROFUN_10829	A0A2P6NKZ4	A0A2P6NCP3	Uncharacterized protein.	Spatacsin_C domain-containing protein.	0.561
PROFUN_09281	PROFUN_14049	A0A2P6NKZ4	A0A2P6N248	Uncharacterized protein.	Cyclin-G-associated kinase.	0.691
PROFUN_10164	PROFUN_10829	A0A2P6NEK4	A0A2P6NCP3	Uncharacterized protein.	Spatacsin_C domain-containing protein.	0.582
PROFUN_10576	PROFUN_05600	A0A2P6NCZ1	A0A2P6N078	Alpha/beta hydrolase fold-1 domain-containing protein.	Spartin-like protein.	0.520
PROFUN_10576	PROFUN_10829	A0A2P6NCZ1	A0A2P6NCP3	Alpha/beta hydrolase fold-1 domain-containing protein.	Spatacsin_C domain-containing protein.	0.559
PROFUN_10829	PROFUN_02281	A0A2P6NCP3	A0A2P6NYG7	Spatacsin_C domain-containing protein.	Uncharacterized protein.	0.582
PROFUN_10829	PROFUN_02591	A0A2P6NCP3	A0A2P6MPH2	Spatacsin_C domain-containing protein.	SAC domain-containing protein.	0.510

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

16

PPI enrichment p-value:

4.27e-14

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050658

RNA transport

5 of 80

1.83

2.08

2.72e-05

GO:0051028

mRNA transport

4 of 65

1.82

1.75

0.00020

GO:0006913

Nucleocytoplasmic transport

4 of 92

1.67

1.45

0.00066

GO:1904263

Positive regulation of TORC1 signaling

2 of 9

2.38

1.09

0.0097

GO:0008104

Protein localization

6 of 489

1.12

0.98

0.00080

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005198

Structural molecule activity

7 of 234

1.51

2.12

6.52e-07

GO:0017056

Structural constituent of nuclear pore

3 of 17

2.28

1.73

0.00054

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005643

Nuclear pore

5 of 38

2.15

3.25

1.89e-07

GO:0031965

Nuclear membrane

3 of 54

1.78

1.15

0.0048

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1738

Structural constituent of nuclear pore, and Sec13/Seh1 family

4 of 17

2.4

2.8

4.41e-06

CL:1743

Nup133 N terminal like, and mRNA transport

3 of 6

2.73

2.6

1.63e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03013

RNA transport

5 of 173

1.49

1.66

4.65e-05

map00254

Aflatoxin biosynthesis

2 of 21

2.01

0.97

0.0147

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-4085377

SUMOylation of SUMOylation proteins

4 of 29

2.17

2.43

1.54e-05

MAP-9615933

Postmitotic nuclear pore complex (NPC) reformation

3 of 20

2.21

1.73

0.00050

MAP-2995410

Nuclear Envelope (NE) Reassembly

3 of 33

1.99

1.57

0.00080

MAP-3108232

SUMO E3 ligases SUMOylate target proteins

4 of 107

1.6

1.39

0.00073

MAP-2990846

SUMOylation

4 of 118

1.56

1.35

0.00079

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005643

Nuclear pore

4 of 52

1.92

1.97

8.11e-05

GOCC:0005635

Nuclear envelope

5 of 131

1.61

1.72

8.11e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0653

Protein transport

3 of 63

1.71

1.07

0.0064

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR037363

Sec13/Seh1 family

2 of 2

3.03

1.03

0.0140

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