PROFUN_04758 protein (Planoprotostelium fungivorum)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

PROFUN_04758

Uncharacterized protein. (267 aa)

Predicted Functional Partners:

PROFUN_07405

0.520

PROFUN_07406

0.520

PROFUN_13106

0.520

PROFUN_11196

0.520

PROFUN_01144

0.520

PROFUN_01159

0.520

PROFUN_08909

0.520

PROFUN_07426

0.520

PROFUN_02798

0.520

PROFUN_00314

0.520

Your Current Organism:

Planoprotostelium fungivorum

NCBI taxonomy Id: 1890364
Other names: P. fungivorum, Planoprotostelium fungivorum Hillmann, Ferling, Novohradska & Gloeckner 2017, Protostelium sp. Jena Gg-2016a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PROFUN_00314	PROFUN_04758	A0A2P6NY19	A0A2P6NG34	ATPase AAA.	Uncharacterized protein.	0.520
PROFUN_01144	PROFUN_04758	A0A2P6NCF6	A0A2P6NG34	Cell division cycle protein 48.	Uncharacterized protein.	0.520
PROFUN_01144	PROFUN_08909	A0A2P6NCF6	A0A2P6NIT8	Cell division cycle protein 48.	Spermatogenesis-associated protein 5-like.	0.834
PROFUN_01159	PROFUN_04758	A0A2P6NCK2	A0A2P6NG34	AAA domain-containing protein.	Uncharacterized protein.	0.520
PROFUN_02798	PROFUN_04758	A0A2P6NXM5	A0A2P6NG34	AAA domain-containing protein.	Uncharacterized protein.	0.520
PROFUN_04758	PROFUN_00314	A0A2P6NG34	A0A2P6NY19	Uncharacterized protein.	ATPase AAA.	0.520
PROFUN_04758	PROFUN_01144	A0A2P6NG34	A0A2P6NCF6	Uncharacterized protein.	Cell division cycle protein 48.	0.520
PROFUN_04758	PROFUN_01159	A0A2P6NG34	A0A2P6NCK2	Uncharacterized protein.	AAA domain-containing protein.	0.520
PROFUN_04758	PROFUN_02798	A0A2P6NG34	A0A2P6NXM5	Uncharacterized protein.	AAA domain-containing protein.	0.520
PROFUN_04758	PROFUN_07405	A0A2P6NG34	A0A2P6MTH3	Uncharacterized protein.	Uncharacterized protein.	0.520
PROFUN_04758	PROFUN_07406	A0A2P6NG34	A0A2P6MTI3	Uncharacterized protein.	Uncharacterized protein.	0.520
PROFUN_04758	PROFUN_07426	A0A2P6NG34	A0A2P6NLH3	Uncharacterized protein.	AAA family ATPase.	0.520
PROFUN_04758	PROFUN_08909	A0A2P6NG34	A0A2P6NIT8	Uncharacterized protein.	Spermatogenesis-associated protein 5-like.	0.520
PROFUN_04758	PROFUN_11196	A0A2P6NG34	A0A2P6NAV4	Uncharacterized protein.	AAA domain-containing protein.	0.520
PROFUN_04758	PROFUN_13106	A0A2P6NG34	A0A2P6N5C1	Uncharacterized protein.	SAP domain-containing protein.	0.520
PROFUN_07405	PROFUN_04758	A0A2P6MTH3	A0A2P6NG34	Uncharacterized protein.	Uncharacterized protein.	0.520
PROFUN_07406	PROFUN_04758	A0A2P6MTI3	A0A2P6NG34	Uncharacterized protein.	Uncharacterized protein.	0.520
PROFUN_07426	PROFUN_04758	A0A2P6NLH3	A0A2P6NG34	AAA family ATPase.	Uncharacterized protein.	0.520
PROFUN_08909	PROFUN_01144	A0A2P6NIT8	A0A2P6NCF6	Spermatogenesis-associated protein 5-like.	Cell division cycle protein 48.	0.834
PROFUN_08909	PROFUN_04758	A0A2P6NIT8	A0A2P6NG34	Spermatogenesis-associated protein 5-like.	Uncharacterized protein.	0.520

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

30

average node degree:

5.45

avg. local clustering coefficient:

0.88

expected number of edges:

11

PPI enrichment p-value:

9.52e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006096

Glycolytic process

5 of 10

2.28

3.42

1.46e-07

GO:0006006

Glucose metabolic process

3 of 11

2.02

1.88

0.00017

GO:0010133

Proline catabolic process to glutamate

3 of 13

1.95

1.77

0.00025

GO:0016310

Phosphorylation

7 of 148

1.26

1.59

1.30e-06

GO:1901575

Organic substance catabolic process

8 of 195

1.2

1.54

3.32e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016620

Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

3 of 21

1.74

0.89

0.0174

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:26388970

(2015) High quality draft genomic sequence of Flavihumibacter solisilvae 3-3(T).

2 of 20

1.58

1.17

0.0028

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1300

Pentose phosphate pathway, and Glycolysis

6 of 22

2.02

3.46

2.01e-08

CL:1305

Glycolysis

4 of 7

2.34

3.06

1.08e-06

CL:1230

Carbon metabolism, and Dehydrogenase, E1 component

7 of 57

1.67

2.8

2.01e-08

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00010

Glycolysis / Gluconeogenesis

9 of 53

1.81

4.37

1.18e-13

map01200

Carbon metabolism

7 of 101

1.42

2.12

7.53e-08

map00680

Methane metabolism

3 of 23

1.7

1.43

0.00084

map00410

beta-Alanine metabolism

2 of 5

2.19

1.39

0.0023

map00561

Glycerolipid metabolism

3 of 26

1.65

1.37

0.00098

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0324

Glycolysis

5 of 8

2.38

4.01

1.09e-08

KW-0312

Gluconeogenesis

2 of 4

2.28

1.09

0.0095

KW-0413

Isomerase

3 of 68

1.23

0.59

0.0470

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00171

Aldehyde dehydrogenase family

3 of 14

1.91

1.16

0.0053

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR016160

Aldehyde dehydrogenase, cysteine active site

3 of 8

2.16

1.31

0.0033

IPR016163

Aldehyde dehydrogenase, C-terminal

3 of 14

1.91

1.12

0.0067

IPR016162

Aldehyde dehydrogenase, N-terminal

3 of 14

1.91

1.12

0.0067

IPR015590

Aldehyde dehydrogenase domain

3 of 14

1.91

1.12

0.0067

IPR016161

Aldehyde/histidinol dehydrogenase

3 of 15

1.88

1.11

0.0067

(more ...)

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