STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROFUN_09244SET domain-containing protein. (693 aa)    
Predicted Functional Partners:
PROFUN_08055
WD_REPEATS_REGION domain-containing protein.
    
 0.632
PROFUN_12747
Set1/Ash2 histone methyltransferase complex subunit ASH2.
    
 0.615
PROFUN_06467
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.583
PROFUN_05798
Small nuclear ribonucleoprotein G.
    
 0.583
PROFUN_06887
WD-40 repeat-containing protein.
    
 0.565
PROFUN_01513
WD_REPEATS_REGION domain-containing protein.
    
 0.565
PROFUN_12102
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
   
 0.534
PROFUN_15761
Retinoblastoma-binding protein 5.
    
 0.525
PROFUN_11501
WD_REPEATS_REGION domain-containing protein.
    
 0.525
PROFUN_12939
Proteasome 26S non-ATPase subunit 3-like.
    
 0.519
Your Current Organism:
Planoprotostelium fungivorum
NCBI taxonomy Id: 1890364
Other names: P. fungivorum, Planoprotostelium fungivorum Hillmann, Ferling, Novohradska & Gloeckner 2017, Protostelium sp. Jena Gg-2016a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.