PROFUN_07087 protein (Planoprotostelium fungivorum)

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Predicted Interactions

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Score

PROFUN_07087

Acyl-coenzyme A thioesterase 9, mitochondrial-like. (1039 aa)

Predicted Functional Partners:

PROFUN_05870

0.816

PROFUN_04474

0.657

PROFUN_09634

0.645

PROFUN_12348

0.645

PROFUN_03730

0.645

PROFUN_03771

0.559

PROFUN_01253

0.559

PROFUN_14262

0.549

PROFUN_08310

0.549

PROFUN_05869

0.549

Your Current Organism:

Planoprotostelium fungivorum

NCBI taxonomy Id: 1890364
Other names: P. fungivorum, Planoprotostelium fungivorum Hillmann, Ferling, Novohradska & Gloeckner 2017, Protostelium sp. Jena Gg-2016a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PROFUN_01253	PROFUN_03730	A0A2P6NZL6	A0A2P6NDL0	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.892
PROFUN_01253	PROFUN_04474	A0A2P6NZL6	A0A2P6NVU7	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; Belongs to the enoyl-CoA hydratase/isomerase family.	ETF domain-containing protein.	0.669
PROFUN_01253	PROFUN_05869	A0A2P6NZL6	A0A2P6NKP9	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.522
PROFUN_01253	PROFUN_05870	A0A2P6NZL6	A0A2P6NKN4	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; Belongs to the enoyl-CoA hydratase/isomerase family.	Malate synthase.	0.902
PROFUN_01253	PROFUN_07087	A0A2P6NZL6	A0A2P6NN57	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; Belongs to the enoyl-CoA hydratase/isomerase family.	Acyl-coenzyme A thioesterase 9, mitochondrial-like.	0.559
PROFUN_01253	PROFUN_08310	A0A2P6NZL6	A0A2P6NK09	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.522
PROFUN_01253	PROFUN_09634	A0A2P6NZL6	A0A2P6MNV9	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase NAD-binding protein.	0.628
PROFUN_01253	PROFUN_12348	A0A2P6NZL6	A0A2P6N9F5	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; Belongs to the enoyl-CoA hydratase/isomerase family.	Electron transfer flavoprotein subunit beta-like isoform 1.	0.707
PROFUN_01253	PROFUN_14262	A0A2P6NZL6	A0A2P6N0P2	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; Belongs to the enoyl-CoA hydratase/isomerase family.	WD_REPEATS_REGION domain-containing protein.	0.522
PROFUN_03730	PROFUN_01253	A0A2P6NDL0	A0A2P6NZL6	Uncharacterized protein.	Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; Belongs to the enoyl-CoA hydratase/isomerase family.	0.892
PROFUN_03730	PROFUN_03771	A0A2P6NDL0	A0A2P6NDS0	Uncharacterized protein.	Uncharacterized protein.	0.731
PROFUN_03730	PROFUN_04474	A0A2P6NDL0	A0A2P6NVU7	Uncharacterized protein.	ETF domain-containing protein.	0.820
PROFUN_03730	PROFUN_05869	A0A2P6NDL0	A0A2P6NKP9	Uncharacterized protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.628
PROFUN_03730	PROFUN_05870	A0A2P6NDL0	A0A2P6NKN4	Uncharacterized protein.	Malate synthase.	0.716
PROFUN_03730	PROFUN_07087	A0A2P6NDL0	A0A2P6NN57	Uncharacterized protein.	Acyl-coenzyme A thioesterase 9, mitochondrial-like.	0.645
PROFUN_03730	PROFUN_08310	A0A2P6NDL0	A0A2P6NK09	Uncharacterized protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.628
PROFUN_03730	PROFUN_09634	A0A2P6NDL0	A0A2P6MNV9	Uncharacterized protein.	3-hydroxyacyl-CoA dehydrogenase NAD-binding protein.	0.763
PROFUN_03730	PROFUN_12348	A0A2P6NDL0	A0A2P6N9F5	Uncharacterized protein.	Electron transfer flavoprotein subunit beta-like isoform 1.	0.755
PROFUN_03730	PROFUN_14262	A0A2P6NDL0	A0A2P6N0P2	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.628
PROFUN_03771	PROFUN_03730	A0A2P6NDS0	A0A2P6NDL0	Uncharacterized protein.	Uncharacterized protein.	0.731

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

33

average node degree:

6

avg. local clustering coefficient:

0.934

expected number of edges:

11

PPI enrichment p-value:

1.52e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006378

mRNA polyadenylation

6 of 14

2.33

4.34

1.48e-09

GO:0006379

mRNA cleavage

4 of 15

2.13

2.34

2.16e-05

GO:0006303

Double-strand break repair via nonhomologous end joining

4 of 19

2.02

2.16

4.09e-05

GO:0071481

Cellular response to X-ray

2 of 2

2.7

1.33

0.0038

GO:0071480

Cellular response to gamma radiation

2 of 2

2.7

1.33

0.0038

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003684

Damaged DNA binding

3 of 22

1.84

1.05

0.0087

GO:0003676

Nucleic acid binding

9 of 914

0.69

0.51

0.0050

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005849

mRNA cleavage factor complex

6 of 16

2.28

4.4

7.26e-10

GO:0005847

mRNA cleavage and polyadenylation specificity factor complex

5 of 13

2.29

3.68

3.85e-08

GO:0043564

Ku70:Ku80 complex

2 of 2

2.7

1.45

0.0023

GO:0140513

Nuclear protein-containing complex

10 of 622

0.91

0.98

9.84e-07

GO:0000785

Chromatin

6 of 288

1.02

0.86

0.0011

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4200

mRNA polyadenylation, and PTW/PP1 phosphatase complex

6 of 17

2.25

4.29

1.09e-09

CL:2752

Non-homologous end-joining

4 of 5

2.6

3.43

3.34e-07

CL:4201

mRNA cleavage and polyadenylation specificity factor complex, and PTW/PP1 phosphatase complex

4 of 10

2.3

2.91

1.98e-06

CL:4204

Beta-Casp domain, and mRNA cleavage and polyadenylation specificity factor complex

2 of 5

2.3

1.11

0.0089

CL:4221

mRNA polyadenylation

2 of 6

2.22

1.06

0.0105

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03450

Non-homologous end-joining

4 of 11

2.26

3.07

7.83e-07

map03015

mRNA surveillance pathway

7 of 71

1.7

3.02

3.63e-09

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-77595

Processing of Intronless Pre-mRNAs

5 of 16

2.2

3.29

1.85e-07

MAP-75067

Processing of Capped Intronless Pre-mRNA

5 of 19

2.12

3.21

1.92e-07

MAP-73856

RNA Polymerase II Transcription Termination

3 of 26

1.76

1.1

0.0060

MAP-72203

Processing of Capped Intron-Containing Pre-mRNA

5 of 194

1.11

0.79

0.0060

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005849

mRNA cleavage factor complex

6 of 16

2.28

4.39

7.58e-10

GOCC:0005847

mRNA cleavage and polyadenylation specificity factor complex

5 of 12

2.32

3.76

2.91e-08

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02735

Ku70/Ku80 beta-barrel domain

2 of 2

2.7

1.01

0.0146

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR016194

SPOC-like, C-terminal domain superfamily

2 of 2

2.7

0.75

0.0435

IPR006164

Ku70/Ku80 beta-barrel domain

2 of 2

2.7

0.75

0.0435

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