STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROFUN_05094Uncharacterized protein. (462 aa)    
Predicted Functional Partners:
PROFUN_01428
Transcription initiation factor TFIID subunit.
    
 
 0.683
PROFUN_06467
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.575
PROFUN_08787
DNA methyltransferase 1 associated protein 1.
    
 
 0.575
PROFUN_05798
Small nuclear ribonucleoprotein G.
    
 
 0.575
PROFUN_07491
Transcription factor E2F.
    
 
 0.565
PROFUN_09300
Transcription initiation factor TFIID subunit 1.
    
 
 0.524
PROFUN_03490
U3 small nucleolar RNA-interacting protein 2-like.
    
 
 0.467
PROFUN_08345
RuvB-like helicase; Belongs to the RuvB family.
    
 
 0.465
PROFUN_03000
RuvB-like helicase; Belongs to the RuvB family.
    
 
 0.465
PROFUN_08738
Craniofacial development protein 1.
    
 
 0.445
Your Current Organism:
Planoprotostelium fungivorum
NCBI taxonomy Id: 1890364
Other names: P. fungivorum, Planoprotostelium fungivorum Hillmann, Ferling, Novohradska & Gloeckner 2017, Protostelium sp. Jena Gg-2016a
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