STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROFUN_02610AB hydrolase-1 domain-containing protein. (450 aa)    
Predicted Functional Partners:
PROFUN_11807
D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.846
PROFUN_07872
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.846
PROFUN_00709
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.846
PROFUN_05660
Phosphoserine phosphatase SerB.
  
 
 0.821
PROFUN_00503
Uncharacterized protein; Belongs to the HisA/HisF family.
  
  
 0.790
PROFUN_12374
Threonine synthase-like 1.
   
 0.753
PROFUN_10075
Tryptophane synthase.
   
  
 0.740
PROFUN_13760
Gamma-glutamyl phosphate reductase.
  
  
 0.738
PROFUN_13018
Alkaline phosphatase.
     
 0.646
PROFUN_10752
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.633
Your Current Organism:
Planoprotostelium fungivorum
NCBI taxonomy Id: 1890364
Other names: P. fungivorum, Planoprotostelium fungivorum Hillmann, Ferling, Novohradska & Gloeckner 2017, Protostelium sp. Jena Gg-2016a
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