STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROFUN_04007Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2346 aa)    
Predicted Functional Partners:
PROFUN_10488
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 0.957
PROFUN_14692
Putative nonsense-mediated mRNA decay protein.
    
 0.949
PROFUN_07932
WD40 repeat-containing protein.
    
 0.915
PROFUN_07409
Ras-related GTP-binding protein.
    
 0.897
NTH1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.
    
 0.879
PROFUN_10522
Telomere_reg-2 domain-containing protein.
    
 0.844
PROFUN_07686
Regulatory-associated protein of mTOR isoform 2.
   
 0.841
PROFUN_09633
Regulatory-associated protein of mTOR-like.
   
 0.841
PROFUN_15617
Cytosolic regulator of adenylyl cyclase.
   
 0.837
PROFUN_06212
Cytosolic regulator of adenylyl cyclase.
   
 0.837
Your Current Organism:
Planoprotostelium fungivorum
NCBI taxonomy Id: 1890364
Other names: P. fungivorum, Planoprotostelium fungivorum Hillmann, Ferling, Novohradska & Gloeckner 2017, Protostelium sp. Jena Gg-2016a
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