STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROFUN_02102Signal transduction histidine kinase. (920 aa)    
Predicted Functional Partners:
PROFUN_11385
Multi-sensor hybrid histidine kinase.
 
  
  0.445
PROFUN_09061
Putative DNA binding protein.
   
 0.440
PROFUN_03694
Diguanylate cyclase.
 
  
  0.434
PROFUN_14952
Uncharacterized protein.
    
 0.426
PROFUN_06411
3-methyl-2-oxobutanoate dehydrogenase.
    
 0.426
PROFUN_03657
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.426
PROFUN_04963
Uncharacterized protein.
    
 0.421
PROFUN_13617
Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
    
 
 0.412
PROFUN_15288
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.403
PROFUN_03530
Dihydrolipoamide succinyltransferase.
    
 0.403
Your Current Organism:
Planoprotostelium fungivorum
NCBI taxonomy Id: 1890364
Other names: P. fungivorum, Planoprotostelium fungivorum Hillmann, Ferling, Novohradska & Gloeckner 2017, Protostelium sp. Jena Gg-2016a
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