node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APZ96997.1 | gcvH_1 | Fuma_06674 | Fuma_00152 | Dihydrolipoyl dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.963 |
APZ96997.1 | gcvH_2 | Fuma_06674 | Fuma_02749 | Dihydrolipoyl dehydrogenase. | Glycine cleavage system H protein. | 0.953 |
APZ96997.1 | gcvP | Fuma_06674 | Fuma_00153 | Dihydrolipoyl dehydrogenase. | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.936 |
APZ96997.1 | gcvT | Fuma_06674 | Fuma_00151 | Dihydrolipoyl dehydrogenase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.942 |
APZ96997.1 | glyA | Fuma_06674 | Fuma_02162 | Dihydrolipoyl dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.913 |
APZ96997.1 | lpdA | Fuma_06674 | Fuma_00597 | Dihydrolipoyl dehydrogenase. | Dihydrolipoyl dehydrogenase. | 0.911 |
APZ96997.1 | pucG | Fuma_06674 | Fuma_04774 | Dihydrolipoyl dehydrogenase. | Purine catabolism protein PucG. | 0.901 |
gcvH_1 | APZ96997.1 | Fuma_00152 | Fuma_06674 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase. | 0.963 |
gcvH_1 | gcvH_2 | Fuma_00152 | Fuma_02749 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system H protein. | 0.918 |
gcvH_1 | gcvP | Fuma_00152 | Fuma_00153 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH_1 | gcvT | Fuma_00152 | Fuma_00151 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvH_1 | glyA | Fuma_00152 | Fuma_02162 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.961 |
gcvH_1 | lpdA | Fuma_00152 | Fuma_00597 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase. | 0.961 |
gcvH_1 | pucG | Fuma_00152 | Fuma_04774 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Purine catabolism protein PucG. | 0.913 |
gcvH_2 | APZ96997.1 | Fuma_02749 | Fuma_06674 | Glycine cleavage system H protein. | Dihydrolipoyl dehydrogenase. | 0.953 |
gcvH_2 | gcvH_1 | Fuma_02749 | Fuma_00152 | Glycine cleavage system H protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.918 |
gcvH_2 | gcvP | Fuma_02749 | Fuma_00153 | Glycine cleavage system H protein. | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH_2 | gcvT | Fuma_02749 | Fuma_00151 | Glycine cleavage system H protein. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvH_2 | glyA | Fuma_02749 | Fuma_02162 | Glycine cleavage system H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.961 |
gcvH_2 | lpdA | Fuma_02749 | Fuma_00597 | Glycine cleavage system H protein. | Dihydrolipoyl dehydrogenase. | 0.954 |