xynB protein (Fuerstia marisgermanicae) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

xynB

Endo-1,4-beta-xylanase B. (1152 aa)

Predicted Functional Partners:

abn-ts

0.849

APZ93488.1

0.782

APZ93035.1

0.774

APZ94387.1

0.774

APZ95501.1

0.774

APZ96338.1

0.728

APZ93382.1

0.714

rhgT

0.714

APZ93383.1

0.656

APZ92993.1

0.655

Your Current Organism:

Fuerstia marisgermanicae

NCBI taxonomy Id: 1891926
Other names: DSM 27554, F. marisgermanicae, LMG 27831, LMG:27831, Planctomycetes bacterium NH11, strain NH11

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ92993.1	abn-ts	Fuma_02605	Fuma_02988	Hypothetical protein.	Intracellular endo-alpha-(1->5)-L-arabinanase.	0.667
APZ92993.1	rhgT	Fuma_02605	Fuma_06239	Hypothetical protein.	Rhamnogalacturonan acetylesterase RhgT.	0.740
APZ92993.1	xynB	Fuma_02605	Fuma_02998	Hypothetical protein.	Endo-1,4-beta-xylanase B.	0.655
APZ93035.1	xynB	Fuma_02648	Fuma_02998	Thiol:disulfide interchange protein precursor.	Endo-1,4-beta-xylanase B.	0.774
APZ93382.1	APZ93383.1	Fuma_02999	Fuma_03000	Hypothetical protein.	Hypothetical protein.	0.709
APZ93382.1	xynB	Fuma_02999	Fuma_02998	Hypothetical protein.	Endo-1,4-beta-xylanase B.	0.714
APZ93383.1	APZ93382.1	Fuma_03000	Fuma_02999	Hypothetical protein.	Hypothetical protein.	0.709
APZ93383.1	xynB	Fuma_03000	Fuma_02998	Hypothetical protein.	Endo-1,4-beta-xylanase B.	0.656
APZ93488.1	xynB	Fuma_03106	Fuma_02998	Thiol:disulfide interchange protein precursor.	Endo-1,4-beta-xylanase B.	0.782
APZ94387.1	xynB	Fuma_04019	Fuma_02998	Thioredoxin-related protein.	Endo-1,4-beta-xylanase B.	0.774
APZ95501.1	xynB	Fuma_05159	Fuma_02998	Thioredoxin-related protein.	Endo-1,4-beta-xylanase B.	0.774
APZ96338.1	abn-ts	Fuma_06006	Fuma_02988	Hypothetical protein.	Intracellular endo-alpha-(1->5)-L-arabinanase.	0.631
APZ96338.1	rhgT	Fuma_06006	Fuma_06239	Hypothetical protein.	Rhamnogalacturonan acetylesterase RhgT.	0.685
APZ96338.1	xynB	Fuma_06006	Fuma_02998	Hypothetical protein.	Endo-1,4-beta-xylanase B.	0.728
abn-ts	APZ92993.1	Fuma_02988	Fuma_02605	Intracellular endo-alpha-(1->5)-L-arabinanase.	Hypothetical protein.	0.667
abn-ts	APZ96338.1	Fuma_02988	Fuma_06006	Intracellular endo-alpha-(1->5)-L-arabinanase.	Hypothetical protein.	0.631
abn-ts	xynB	Fuma_02988	Fuma_02998	Intracellular endo-alpha-(1->5)-L-arabinanase.	Endo-1,4-beta-xylanase B.	0.849
rhgT	APZ92993.1	Fuma_06239	Fuma_02605	Rhamnogalacturonan acetylesterase RhgT.	Hypothetical protein.	0.740
rhgT	APZ96338.1	Fuma_06239	Fuma_06006	Rhamnogalacturonan acetylesterase RhgT.	Hypothetical protein.	0.685
rhgT	xynB	Fuma_06239	Fuma_02998	Rhamnogalacturonan acetylesterase RhgT.	Endo-1,4-beta-xylanase B.	0.714

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

46

average node degree:

8.36

avg. local clustering coefficient:

0.921

expected number of edges:

45

PPI enrichment p-value:

0.441

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0007165

Signal transduction

8 of 345

1.32

1.75

5.80e-07

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016772

Transferase activity, transferring phosphorus-containing groups

9 of 616

1.12

1.35

7.02e-07

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

7 of 935

0.82

0.68

0.00090

GO:0016021

Integral component of membrane

9 of 1627

0.69

0.57

0.00061

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5063

Mixed, incl. Serpin, conserved site, and Two-component regulatory system

5 of 6

2.87

4.98

5.26e-10

CL:4333

PAS domain, and GAF-like domain superfamily

6 of 37

2.16

4.05

2.09e-09

CL:4344

PAS-associated, C-terminal, and PAS fold

4 of 11

2.51

3.59

1.30e-07

CL:4335

PAS-associated, C-terminal, and GAF-like domain superfamily

5 of 32

2.14

3.5

4.45e-08

CL:4348

PAS fold, and PAS fold-3

2 of 5

2.55

1.51

0.0017

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

8 of 826

0.94

0.91

4.63e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016020

Membrane

7 of 1188

0.72

0.44

0.0291

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

7 of 181

1.54

2.39

5.75e-08

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000014

PAS domain

5 of 52

1.93

2.81

5.90e-07

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

7 of 123

1.71

2.79

4.09e-08

IPR036097

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily

7 of 129

1.69

2.75

4.09e-08

IPR035965

PAS domain superfamily

5 of 55

1.91

2.75

6.91e-07

IPR004358

Signal transduction histidine kinase-related protein, C-terminal

7 of 133

1.67

2.72

4.09e-08

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00388

His Kinase A (phosphoacceptor) domain

7 of 133

1.67

2.92

5.67e-09

SM00387

Histidine kinase-like ATPases

7 of 149

1.62

2.79

6.11e-09

SM00448

cheY-homologous receiver domain

7 of 173

1.56

2.58

1.12e-08

SM00091

PAS domain

4 of 47

1.88

2.31

9.09e-06

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

3 of 34

1.9

1.73

0.00028

(more ...)

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