STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHE23913.1Rna polymerase sigma factor 70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (276 aa)    
Predicted Functional Partners:
rpoC
Rna polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.999
rpoB
Rna polymerases beta chain signature; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.999
SHE23912.1
Putative zinc-finger.
  
 
 0.971
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.878
rpoZ
Rna polymerase subunit omega/k/rpb6; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.878
sigA
Rna polymerase sigma-70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
  
 0.848
SHE24540.1
Hypothetical protein.
    
   0.696
SHE23914.1
Doxx.
  
    0.662
SHE25931.1
Serine/threonine-protein kinase active site.
   
 
 0.645
SHE26603.1
Pyridine nucleotide-disulphide oxidoreductase class-ii.
     
 0.589
Your Current Organism:
Actinomyces glycerinitolerans
NCBI taxonomy Id: 1892869
Other names: A. glycerinitolerans, DSM 10377, TISTR 2318, strain G10
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