STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHE24719.1Alpha/beta hydrolase fold-1. (282 aa)    
Predicted Functional Partners:
SHE23804.1
Hypothetical protein.
 
      0.899
SHE24718.1
Hypothetical protein.
 
  0.896
SHE26121.1
Beta-ketoacyl synthase active site.
  
 
 0.879
acpP
Phosphopantetheine attachment site; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.870
SHE24756.1
Drtgg; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.770
guaB
Imp dehydrogenase / gmp reductase signature; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.638
menD
Menaquinone biosynthesis protein mend; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
  
 
 0.621
guaA
Anthranilate synthase component ii signature; Catalyzes the synthesis of GMP from XMP.
   
  0.602
atpD
Atp synthase alpha and beta subunits signature; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
   
  0.590
atpH
Atpase oscp/delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
    
  0.586
Your Current Organism:
Actinomyces glycerinitolerans
NCBI taxonomy Id: 1892869
Other names: A. glycerinitolerans, DSM 10377, TISTR 2318, strain G10
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