STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFX97003.1DNA polymerase-3 subunit epsilon. (243 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.987
SFY31120.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 0.985
SFX16288.1
DNA polymerase III, delta subunit.
  
 
 0.974
SFX04657.1
DNA polymerase III, alpha subunit.
   
 0.940
SFX78096.1
DNA polymerase-3 subunit alpha.
   
 0.940
SFY23208.1
DNA polymerase-3 subunit delta'.
   
 0.934
SFX81570.1
DNA polymerase III sliding clamp (beta) subunit, PCNA homolog.
  
 0.925
SFX49144.1
DNA polymerase-3 subunit epsilon.
  
  
 
0.918
SFX43471.1
Error-prone DNA polymerase; Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
   
 0.872
SFX96987.1
Hypothetical protein.
       0.790
Your Current Organism:
Streptomyces atratus
NCBI taxonomy Id: 1893
Other names: ATCC 14046, DSM 41673, IFO 3897, JCM 3386, NBRC 3897, NRRL B-16927, S. atratus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.