STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KOG84066.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)    
Predicted Functional Partners:
KOG84065.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.990
KOG84064.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.985
KOG84062.1
DoxX family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.966
KOG84084.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.959
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.917
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.906
KOG71551.1
Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.903
KOG79134.1
Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
     
 0.901
KOG84067.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.892
KOG72651.1
Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.892
Your Current Organism:
Kitasatospora aureofaciens
NCBI taxonomy Id: 1894
Other names: ATCC 10762, ATCC 23884, BCRC 11610, CBS 434.51, CBS 664.68, CCRC 11610, CCRC:11610, CECT 3206, CIP 57.11, DSM 40127, HAMBI 313, HUT 6048, HUT 6097, ICMP 499, IFO 12594, IFO 12843, IFO 3712, ISP 5127, JCM 4008, JCM 4624, K. aureofaciens, KACC 20180, LMG 5968, LMG:5968, NBRC 12594, NBRC 12843, NBRC 3712, NCAIM B.01479, NCIMB 8234, NRRL 2209, NRRL B-5404, NRRL-ISP 5127, NRRL-ISP:5127, NRRL:B:5404, RIA 57, Streptomyces aureifaciens, Streptomyces aureofaciens, Streptomyces aureofaciens subsp. aureofaciens, VKM Ac-771
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