STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KOG84121.1Alkyl/aryl-sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (683 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.861
KOG69339.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.851
KOG67298.1
Ribonuclease Z; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.849
KOG71032.1
Sodium:proton exchanger; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.843
KOG77758.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.832
KOG75692.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.827
KOG69511.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.805
KOG75601.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.777
KOG72306.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.762
KOG75115.1
Sulfate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.753
Your Current Organism:
Kitasatospora aureofaciens
NCBI taxonomy Id: 1894
Other names: ATCC 10762, ATCC 23884, BCRC 11610, CBS 434.51, CBS 664.68, CCRC 11610, CCRC:11610, CECT 3206, CIP 57.11, DSM 40127, HAMBI 313, HUT 6048, HUT 6097, ICMP 499, IFO 12594, IFO 12843, IFO 3712, ISP 5127, JCM 4008, JCM 4624, K. aureofaciens, KACC 20180, LMG 5968, LMG:5968, NBRC 12594, NBRC 12843, NBRC 3712, NCAIM B.01479, NCIMB 8234, NRRL 2209, NRRL B-5404, NRRL-ISP 5127, NRRL-ISP:5127, NRRL:B:5404, RIA 57, Streptomyces aureifaciens, Streptomyces aureofaciens, Streptomyces aureofaciens subsp. aureofaciens, VKM Ac-771
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