Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KOG77933.1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)    
Predicted Functional Partners:
KOG69339.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.976
KOG77935.1
Alkanesulfonate monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.865
KOG77847.1
Alkanesulfonate monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.865
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.865
KOG67892.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.858
KOG83173.1
NADPH-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.849
KOG79684.1
NADPH-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.849
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.845
KOG72310.1
Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.844
KOG77820.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.813
Your Current Organism:
Kitasatospora aureofaciens
NCBI taxonomy Id: 1894
Other names: ATCC 10762, ATCC 23884, BCRC 11610, CBS 434.51, CBS 664.68, CCRC 11610, CCRC:11610, CECT 3206, CIP 57.11, DSM 40127, HAMBI 313, HUT 6048, HUT 6097, ICMP 499, IFO 12594, IFO 12843, IFO 3712, ISP 5127, JCM 4008, JCM 4624, K. aureofaciens, KACC 20180, LMG 5968, LMG:5968, NBRC 12594, NBRC 12843, NBRC 3712, NCAIM B.01479, NCIMB 8234, NRRL 2209, NRRL B-5404, NRRL-ISP 5127, NRRL-ISP:5127, NRRL:B:5404, RIA 57, Streptomyces aureifaciens, Streptomyces aureofaciens, Streptomyces aureofaciens subsp. aureofaciens, VKM Ac-771
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